000009529 001__ 9529
000009529 005__ 20240411150344.0
000009529 0247_ $$2DOI$$a10.6083/hq37vp30d
000009529 037__ $$aIR
000009529 041__ $$aeng
000009529 245__ $$aMaternal and perinatal outcomes of maternal creatine supplementation as a therapy for neonatal encephalopathy
000009529 260__ $$bOregon Health and Science University
000009529 269__ $$a2022
000009529 336__ $$aAbstract
000009529 520__ $$aHypoxic ischemic encephalopathy (HIE) occurs in ~4 per 1000 live term births. Infants that receive current treatments may still develop adverse neurologic outcomes. Maternal gestational creatine supplementation has been proposed as a potential prophylactic neuroprotective therapy, with evidence of reduction in perinatal brain injury in rodent and sheep studies. The current study aims to characterize aspects of creatine synthesis, metabolism, and transport in gestational and neonatal tissues following maternal oral creatine supplementation.
000009529 540__ $$fCC BY
000009529 542__ $$fIn copyright - joint owners
000009529 650__ $$aCreatine$$017178
000009529 650__ $$aCerebral Palsy$$016369
000009529 650__ $$aPregnancy$$024523
000009529 650__ $$aPremature Birth$$036011
000009529 650__ $$aHypoxia-Ischemia, Brain$$032814
000009529 650__ $$aHypoxia, Brain$$016356
000009529 6531_ $$ahypoxic-ischemic encephalopathy
000009529 692__ $$aOregon National Primate Research Center$$041497
000009529 7001_ $$aDimagiba, Yvonne T.$$uOregon Health and Science University$$041354
000009529 7001_ $$aTripathy, Sudeshna$$uOregon Health and Science University$$041354
000009529 7001_ $$aEllery, Stacey J.$$uHudson Medical Research Institute
000009529 7001_ $$aSnow, Rod J.$$uDeakin University
000009529 7001_ $$aWalker, David W.$$uRMIT University
000009529 7001_ $$aSherman, Larry S.$$uOregon Health and Science University$$041354
000009529 7001_ $$aKelleher, Meredith A.$$uOregon Health and Science University$$041354
000009529 711__ $$aResearch Week$$uOregon Health and Science University$$d2022
000009529 8564_ $$91f4a6371-5a6b-4369-85aa-1c2d4c8e51be$$s118882$$uhttps://digitalcollections.ohsu.edu/record/9529/files/Dimagiba-Yvonne-OHSU-ResearchWeek-2022.pdf
000009529 905__ $$a/rest/prod/hq/37/vp/30/hq37vp30d
000009529 980__ $$aResearch Week