000009531 001__ 9531
000009531 005__ 20240415141225.0
000009531 0247_ $$2DOI$$a10.6083/1v53jx65v
000009531 037__ $$aIR
000009531 245__ $$aRelationship between weight restriction and delay discounting in rats
000009531 260__ $$bOregon Health and Science University
000009531 269__ $$a2022
000009531 336__ $$aAbstract
000009531 520__ $$aDelay discounting is a form of impulsive choice in which the perceived value of a reward decreases as delay to reward increases. Increased rates of delay discounting have been associated with a multitude of psychopathologies, including substance use disorders. Translational studies using rodent models have broadened our understanding of this behavior and been used identify potential therapeutic interventions. It is common practice to restrict weight when using animal models to increase both motivation and engagement with the discounting task. Results from this study emphasize the importance of developing a more standardized weight restriction procedure in studies using food restriction as a way to increase animal motivation in discounting tasks. Future research may look to determine the role of feeding times and metabolism on delay discounting rates.
000009531 540__ $$fCC BY
000009531 542__ $$fIn copyright - joint owners
000009531 650__ $$aDelay Discounting$$040692
000009531 650__ $$aSubstance-Related Disorders$$032029
000009531 6531_ $$aadjusting amount
000009531 6531_ $$aneuroeconomics
000009531 6531_ $$aweight restriction
000009531 691__ $$aSchool of Medicine$$041369
000009531 692__ $$aDepartment of Behavioral Neuroscience$$041394
000009531 7001_ $$aFaraca, Jessica$$uOregon Health and Science University$$041354
000009531 7001_ $$aZepcan, Enedina$$uOregon Health and Science University$$041354
000009531 7001_ $$aMitchell, Suzanne H.$$uOregon Health and Science University$$041354
000009531 711__ $$aResearch Week$$uOregon Health and Science University
000009531 8564_ $$9ea33ab1b-5545-4423-a30a-323a7a3de1c9$$s384007$$uhttps://digitalcollections.ohsu.edu/record/9531/files/Faraca-Jessica-OHSU-ResearchWeek-2022.pdf
000009531 905__ $$a/rest/prod/1v/53/jx/65/1v53jx65v
000009531 980__ $$aResearch Week