000009545 001__ 9545
000009545 005__ 20240328074522.0
000009545 0247_ $$2DOI$$a10.6083/z316q237s
000009545 037__ $$aIR
000009545 041__ $$aeng
000009545 245__ $$aAssociations between GABRA2 genetic  variation, subjective response to acute alcohol intoxication, and the functional connectivity of the reward circuitry
000009545 260__ $$bOregon Health and Science University
000009545 269__ $$a2022
000009545 336__ $$aAbstract
000009545 520__ $$aThe GABRA2 gene encodes a subunit of a GABAA receptor found in the mesolimbic reward circuitry, and modulation of GABAA receptors by alcohol is hypothesized to contribute to the psychotropic properties of the drug. Linkage studies have found a significant correlation between a single nucleotide polymorphism (SNP, rs279858) in the GABRA2 gene and increased risk for alcohol use disorders (AUDs).
000009545 540__ $$fCC BY
000009545 542__ $$fIn copyright - joint owners
000009545 650__ $$aAlcoholism$$014412
000009545 6531_ $$aacute alcohol intoxication
000009545 6531_ $$afunctional connectivity
000009545 6531_ $$ars-fmri
000009545 6531_ $$amesolimbic reward circuitry
000009545 6531_ $$agabra2
000009545 691__ $$aSchool of Medicine$$041369
000009545 692__ $$aDepartment of Psychiatry$$041443
000009545 7001_ $$aHart, Elijah R.$$uOregon Health and Science University$$041354
000009545 7001_ $$aGilbert, Sydney J.$$uOregon Health and Science University$$041354
000009545 7001_ $$aBoyd, Stephen J.$$uOregon Health and Science University$$041354
000009545 7001_ $$aMorales, Angelica M.$$uOregon Health and Science University$$041354
000009545 7001_ $$aMitchell, Suzanne H.$$uOregon Health and Science University$$041354
000009545 7001_ $$aNagel, Bonnie J.$$uOregon Health and Science University$$041354
000009545 711__ $$aResearch Week$$uOregon Health and Science University$$d2022
000009545 8564_ $$9d8f9d32b-2d0f-4166-86e1-97b9e2e5613f$$s35625$$uhttps://digitalcollections.ohsu.edu/record/9545/files/Hart-Elijah-OHSU-ResearchWeek-2022.pdf
000009545 905__ $$a/rest/prod/z3/16/q2/37/z316q237s
000009545 980__ $$aResearch Week