TY  - GEN
N2  - Prenatal diagnoses of congenital heart disease (CHD) is a significant event that causes parental stress and anxiety. The presence of elevated cortisol in a pregnant person's blood can lead to placental transfer of this stress hormone and subsequently downregulate the fetus' own cortisol production through negative feedback mechanisms. Babies with CHD often require very stressful interventions postnatally that necessitate a properly functioning hypothalamic-pituitary-adrenal axis in order to mount a sufficient cortisol mediated stress response. We sought to investigate the relationship between maternal stress during pregnancy and need for neonatal steroids.
DO  - 10.6083/f4752h48r
DO  - DOI
AB  - Prenatal diagnoses of congenital heart disease (CHD) is a significant event that causes parental stress and anxiety. The presence of elevated cortisol in a pregnant person's blood can lead to placental transfer of this stress hormone and subsequently downregulate the fetus' own cortisol production through negative feedback mechanisms. Babies with CHD often require very stressful interventions postnatally that necessitate a properly functioning hypothalamic-pituitary-adrenal axis in order to mount a sufficient cortisol mediated stress response. We sought to investigate the relationship between maternal stress during pregnancy and need for neonatal steroids.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Harmful intrauterine exposure to stress and resulting steroid requirements in infants with congenital heart disease
DA  - 2022
AU  - Katlaps, Isabel
AU  - Ronai, C.
AU  - Kim, A.
AU  - Gutshall, K.
AU  - Valent, A.
AU  - Thornburg, K.
AU  - Madriago, E.
L1  - https://digitalcollections.ohsu.edu/record/9552/files/Katlaps-Isabel-OHSU-ResearchWeek-2022_1_.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2022
ID  - 9552
L4  - https://digitalcollections.ohsu.edu/record/9552/files/Katlaps-Isabel-OHSU-ResearchWeek-2022_1_.pdf
KW  - Obstetrics
KW  - Cardiology
KW  - Pediatrics
KW  - Heart Defects, Congenital
KW  - developmental origins of health and disease
KW  - congenital heart disease
KW  - pediatric cardiology
KW  - steroid treatment
TI  - Harmful intrauterine exposure to stress and resulting steroid requirements in infants with congenital heart disease
Y1  - 2022
L2  - https://digitalcollections.ohsu.edu/record/9552/files/Katlaps-Isabel-OHSU-ResearchWeek-2022_1_.pdf
LK  - https://digitalcollections.ohsu.edu/record/9552/files/Katlaps-Isabel-OHSU-ResearchWeek-2022_1_.pdf
UR  - https://digitalcollections.ohsu.edu/record/9552/files/Katlaps-Isabel-OHSU-ResearchWeek-2022_1_.pdf
ER  -