000009552 001__ 9552
000009552 005__ 20240408144331.0
000009552 0247_ $$2DOI$$a10.6083/f4752h48r
000009552 037__ $$aIR
000009552 041__ $$aeng
000009552 245__ $$aHarmful intrauterine exposure to stress and resulting steroid requirements in infants with congenital heart disease
000009552 260__ $$bOregon Health and Science University
000009552 269__ $$a2022
000009552 336__ $$aAbstract
000009552 520__ $$aPrenatal diagnoses of congenital heart disease (CHD) is a significant event that causes parental stress and anxiety. The presence of elevated cortisol in a pregnant person's blood can lead to placental transfer of this stress hormone and subsequently downregulate the fetus' own cortisol production through negative feedback mechanisms. Babies with CHD often require very stressful interventions postnatally that necessitate a properly functioning hypothalamic-pituitary-adrenal axis in order to mount a sufficient cortisol mediated stress response. We sought to investigate the relationship between maternal stress during pregnancy and need for neonatal steroids.
000009552 540__ $$fCC BY
000009552 542__ $$fIn copyright - joint owners
000009552 650__ $$aObstetrics$$023126
000009552 650__ $$aCardiology$$016143
000009552 650__ $$aPediatrics$$023687
000009552 650__ $$aHeart Defects, Congenital$$019936
000009552 6531_ $$adevelopmental origins of health and disease
000009552 6531_ $$acongenital heart disease
000009552 6531_ $$apediatric cardiology
000009552 6531_ $$asteroid treatment
000009552 691__ $$aSchool of Medicine$$041369
000009552 692__ $$aDepartment of Obstetrics and Gynecology$$041432
000009552 7001_ $$aKatlaps, Isabel$$uOregon Health and Science University$$041354
000009552 7001_ $$aRonai, C.$$uOregon Health and Science University$$041354
000009552 7001_ $$aKim, A.$$uOregon Health and Science University$$041354
000009552 7001_ $$aGutshall, K.$$uOregon Health and Science University$$041354
000009552 7001_ $$aValent, A.$$uOregon Health and Science University$$041354
000009552 7001_ $$aThornburg, K.$$uOregon Health and Science University$$041354
000009552 7001_ $$aMadriago, E.$$uOregon Health and Science University$$041354
000009552 711__ $$aResearch Week$$uOregon Health and Science University$$d2022
000009552 8564_ $$9656d8b25-83a7-4c27-ab77-20ce189e6c65$$s49986$$uhttps://digitalcollections.ohsu.edu/record/9552/files/Katlaps-Isabel-OHSU-ResearchWeek-2022_1_.pdf
000009552 905__ $$a/rest/prod/f4/75/2h/48/f4752h48r
000009552 980__ $$aResearch Week