@article{IR,
      author = {Funahashi, Yoshio and Groat, Tahnee and Hutchens, Michael},
      url = {http://digitalcollections.ohsu.edu/record/9558},
      title = {Cardiac arrest induced systemic ischemia alters phenotype  of renal ischemia reperfusion injury},
      publisher = {Oregon Health and Science University},
      abstract = {Cardiorenal syndrome type 1 (CRS1) is acute kidney injury  (AKI) due to rapid worsening of cardiac function, and is a  common cause of AKI. Ischemic AKI and subsequent chronic  kidney disease (CKD) is mainly investigated by using the  model of renal pedicle clamp (ischemia-reperfusion injury:  IRI) which models renal transplant warm ischemia. However,  results from IRI do not mimic clinical CRS1. We have  previously identified a cardiac-derived soluble factor,  cardiac LIM protein (CSRP3), which mediates renal function.  We hypothesized that the phenotype of AKI-CKD transition  differs between animal models of systemic ischemia and  renal-limited ischemia.},
      number = {IR},
      doi = {https://doi.org/10.6083/pr76f424d},
      recid = {9558},
      address = {2022-04-08},
}