@article{IR,
      author = {Newman, Matthew T. and Baker, Kristina and Joshi, Sunil K.  and Pittsenbarger, Janet and Traer, Elie and Lind, Evan F.  and Druker, Brian J.},
      url = {http://digitalcollections.ohsu.edu/record/9569},
      title = {Early phospho-signaling shifts in Smart BufferTM-preserved  peripheral blood specimens in response to FLT3 inhibitor  therapy},
      publisher = {Oregon Health and Science University},
      abstract = {Identification of druggable mutations in Acute Myeloid  Leukemia (AML), such as FLT3-ITD, has led to the  development of targeted therapies capable of out-performing  cytotoxic chemotherapy. Despite early survival benefits,  most patients with FLT3-ITD AML on trial with the FLT3  inhibitor (FLT3i) gilteritinib still develop treatment  resistance. Critical readout of response to FLT3i as  measured by phospho-signaling is missing for the majority  of these patients. Here, we validated an innovative  approach to obtaining these signatures by leveraging the  Smart BufferTM preservation system for peripheral blood  (PB) specimens integrated with phospho-mass cytometry as  part of the ongoing BeatAML Trial.},
      number = {IR},
      doi = {https://doi.org/10.6083/cn69m508w},
      recid = {9569},
      address = {2022},
}