000009574 001__ 9574 000009574 005__ 20240418083045.0 000009574 0247_ $$2DOI$$a10.6083/mk61rh69c 000009574 037__ $$aIR 000009574 245__ $$aThe role of prophylactic levetiracetam for patients with brain tumors treated in a CNS multidisciplinary clinic for radiation oncology and neurosurgery (RADIANS) and a review of literature 000009574 260__ $$bOregon Health and Science University 000009574 269__ $$a2022 000009574 336__ $$aAbstract 000009574 520__ $$aSeizure incidence following open craniotomy for brain tumors varies in the literature between 5-27%, and following endoscopic endonasal approach ranges from 0-6.25%. Efficacy of prophylactic anticonvulsant therapy in reducing postoperative seizure rates is inconclusive. Furthermore, there is a paucity of evidence for its role during radiotherapy. The RADIANS clinic, a community hospital-based multidisciplinary central nervous system clinic with radiation oncology and neurosurgery, provides a unique model for continuity of care of patients with brain tumors. Prophylactic levetiracetam (LEV) therapy is provided perioperatively, postoperatively, and during radiotherapy. 000009574 540__ $$fCC BY 000009574 542__ $$fIn copyright - joint owners 000009574 650__ $$aRadiation Oncology$$031093 000009574 650__ $$aNeurosurgery$$022875 000009574 650__ $$aLevetiracetam$$012714 000009574 650__ $$aBrain Neoplasms$$015799 000009574 6531_ $$aseizure 000009574 7001_ $$aPang, Brandi W.$$uOregon Health and Science University$$041354 000009574 7001_ $$aBowen, Samantha C.$$uOregon Health and Science University$$041354 000009574 7001_ $$aGheewala, Rohi$$uOregon Health and Science University$$041354 000009574 7001_ $$aHoffman, Alexandra$$uOregon Health and Science University$$041354 000009574 7001_ $$aLucke-Wold, Brandon$$uOregon Health and Science University$$041354 000009574 7001_ $$aPaez, Wencesley A.$$uOregon Health and Science University$$041354 000009574 7001_ $$aMitin, Timur$$uOregon Health and Science University$$041354 000009574 7001_ $$aCiporen, Jeremy N.$$uOregon Health and Science University$$041354 000009574 711__ $$aResearch Week$$uOregon Health and Science University$$d2022 000009574 8564_ $$972d23afc-74b0-44ca-8776-05322517323f$$s64680$$uhttps://digitalcollections.ohsu.edu/record/9574/files/Pang-Brandi-OHSU-ResearchWeek-2022.pdf 000009574 905__ $$a/rest/prod/mk/61/rh/69/mk61rh69c 000009574 980__ $$aResearch Week