TY - GEN N2 - The long-term health effects of methamphetamine including cognitive impairments, anxiety, and depression, which can persist during recovery and are associated with poor treatment outcomes. Thus, biosignatures based on objectively quantifiable blood biomarkers that relate to neuropsychiatric data could be used clinically to monitor recovery. We previously identified seven plasma extracellular vesicle (EV) miRNAs that are differentially expressed in humans with active methamphetamine disorder (MA-ACT) vs. controls (CTL). Here we related the expression of plasma EVs and their miRNAs to measures of neuropsychiatric function. DO - 10.6083/9306sz976 DO - DOI AB - The long-term health effects of methamphetamine including cognitive impairments, anxiety, and depression, which can persist during recovery and are associated with poor treatment outcomes. Thus, biosignatures based on objectively quantifiable blood biomarkers that relate to neuropsychiatric data could be used clinically to monitor recovery. We previously identified seven plasma extracellular vesicle (EV) miRNAs that are differentially expressed in humans with active methamphetamine disorder (MA-ACT) vs. controls (CTL). Here we related the expression of plasma EVs and their miRNAs to measures of neuropsychiatric function. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Relationship between plasma extracellular vesicle miRNAs and measures of neuropsychiatric function in methamphetamine use disorder DA - 2022 AU - Sandau, Ursula S. AU - Duggan, Erika AU - Smith, Sierra J. AU - Huckans, Marilyn AU - Nolan, John P. AU - Loftis, Jennifer M. AU - Saugstad, Julie A. L1 - https://digitalcollections.ohsu.edu/record/9580/files/Sandau-Ursula-OHSU-ResearchWeek-2022.pdf PB - Oregon Health and Science University PY - 2022 ID - 9580 L4 - https://digitalcollections.ohsu.edu/record/9580/files/Sandau-Ursula-OHSU-ResearchWeek-2022.pdf KW - Methamphetamine KW - Plasma KW - Substance-Related Disorders KW - Biomarkers KW - Extracellular Vesicles KW - MIRNA KW - neuropsychiatric function TI - Relationship between plasma extracellular vesicle miRNAs and measures of neuropsychiatric function in methamphetamine use disorder Y1 - 2022 L2 - https://digitalcollections.ohsu.edu/record/9580/files/Sandau-Ursula-OHSU-ResearchWeek-2022.pdf LK - https://digitalcollections.ohsu.edu/record/9580/files/Sandau-Ursula-OHSU-ResearchWeek-2022.pdf UR - https://digitalcollections.ohsu.edu/record/9580/files/Sandau-Ursula-OHSU-ResearchWeek-2022.pdf ER -