000009580 001__ 9580
000009580 005__ 20240415140830.0
000009580 0247_ $$2DOI$$a10.6083/9306sz976
000009580 037__ $$aIR
000009580 245__ $$aRelationship between plasma extracellular vesicle  miRNAs and measures of neuropsychiatric function in methamphetamine use disorder
000009580 260__ $$bOregon Health and Science University
000009580 269__ $$a2022
000009580 336__ $$aAbstract
000009580 520__ $$aThe long-term health effects of methamphetamine including cognitive impairments, anxiety, and depression, which can persist during recovery and are associated with poor treatment outcomes. Thus, biosignatures based on objectively quantifiable blood biomarkers that relate to neuropsychiatric data could be used clinically to monitor recovery. We previously identified seven plasma extracellular vesicle (EV) miRNAs that are differentially expressed in humans with active methamphetamine disorder (MA-ACT) vs. controls (CTL). Here we related the expression of plasma EVs and their miRNAs to measures of neuropsychiatric function.
000009580 540__ $$fCC BY
000009580 542__ $$fIn copyright - joint owners
000009580 650__ $$aMethamphetamine$$022135
000009580 650__ $$aPlasma$$024239
000009580 650__ $$aSubstance-Related Disorders$$032029
000009580 650__ $$aBiomarkers$$028395
000009580 650__ $$aExtracellular Vesicles$$011111
000009580 6531_ $$aMIRNA
000009580 6531_ $$aneuropsychiatric function
000009580 691__ $$aSchool of Medicine$$041369
000009580 692__ $$aDepartment of Anesthesiology and Perioperative Medicine$$041393
000009580 7001_ $$aSandau, Ursula S.$$uOregon Health and Science University$$041354
000009580 7001_ $$aDuggan, Erika$$uOregon Health and Science University$$041354
000009580 7001_ $$aSmith, Sierra J.$$uOregon Health and Science University$$041354
000009580 7001_ $$aHuckans, Marilyn$$uOregon Health and Science University$$041354
000009580 7001_ $$aNolan, John P.$$uOregon Health and Science University$$041354
000009580 7001_ $$aLoftis, Jennifer M.$$uOregon Health and Science University$$041354
000009580 7001_ $$aSaugstad, Julie A.$$uOregon Health and Science University$$041354
000009580 711__ $$aResearch Week$$uOregon Health and Science University$$d2022
000009580 8564_ $$9fc3499a0-ddfe-4a7c-896f-3a56e1c28093$$s55845$$uhttps://digitalcollections.ohsu.edu/record/9580/files/Sandau-Ursula-OHSU-ResearchWeek-2022.pdf
000009580 905__ $$a/rest/prod/93/06/sz/97/9306sz976
000009580 980__ $$aResearch Week