TY  - GEN
N2  - The bone tissue is a complex nanocomposite, organized in a calcified extracellular matrix. Bone autografts remain the gold standard to treat traumatic bone injuries. However, autografts can increase morbidity of the patient?s donor site and has limited availability. On the other hand, bioprinted microgels are attractive biomaterials that offer injectability, tunability, and acts as a cargo to deliver therapeutic proteins and cells. Here, we aim to bioprint and mineralize cell-laden gelatin methacrylate (GelMA) microgels and test the effects of cryopreservation on cell viability for bone tissue engineering applications.
DO  - 10.6083/8623hz558
DO  - DOI
AB  - The bone tissue is a complex nanocomposite, organized in a calcified extracellular matrix. Bone autografts remain the gold standard to treat traumatic bone injuries. However, autografts can increase morbidity of the patient?s donor site and has limited availability. On the other hand, bioprinted microgels are attractive biomaterials that offer injectability, tunability, and acts as a cargo to deliver therapeutic proteins and cells. Here, we aim to bioprint and mineralize cell-laden gelatin methacrylate (GelMA) microgels and test the effects of cryopreservation on cell viability for bone tissue engineering applications.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Biomimetic nanoscale mineralization of bioprinted cell- laden microgels
DA  - 2022
AU  - Sousa, Mauricio
AU  - Balbinot, Gabriela
AU  - Visalakshan, Rauhl
AU  - Subiah, Ramesh
AU  - Bertassoni, Luiz
L1  - https://digitalcollections.ohsu.edu/record/9584/files/Sousa-Mauricio-OHSU-ResearchWeek-2022.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2022
ID  - 9584
L4  - https://digitalcollections.ohsu.edu/record/9584/files/Sousa-Mauricio-OHSU-ResearchWeek-2022.pdf
KW  - Bioprinting
KW  - Bone Regeneration
KW  - Microgels
KW  - Osteocytes
KW  - mineralization
KW  - bone grafting
KW  - autograft
TI  - Biomimetic nanoscale mineralization of bioprinted cell- laden microgels
Y1  - 2022
L2  - https://digitalcollections.ohsu.edu/record/9584/files/Sousa-Mauricio-OHSU-ResearchWeek-2022.pdf
LK  - https://digitalcollections.ohsu.edu/record/9584/files/Sousa-Mauricio-OHSU-ResearchWeek-2022.pdf
UR  - https://digitalcollections.ohsu.edu/record/9584/files/Sousa-Mauricio-OHSU-ResearchWeek-2022.pdf
ER  -