000009584 001__ 9584
000009584 005__ 20240328082640.0
000009584 0247_ $$2DOI$$a10.6083/8623hz558
000009584 037__ $$aIR
000009584 041__ $$aeng
000009584 245__ $$aBiomimetic nanoscale mineralization of bioprinted cell- laden microgels
000009584 260__ $$bOregon Health and Science University
000009584 269__ $$a2022
000009584 336__ $$aAbstract
000009584 520__ $$aThe bone tissue is a complex nanocomposite, organized in a calcified extracellular matrix. Bone autografts remain the gold standard to treat traumatic bone injuries. However, autografts can increase morbidity of the patient?s donor site and has limited availability. On the other hand, bioprinted microgels are attractive biomaterials that offer injectability, tunability, and acts as a cargo to deliver therapeutic proteins and cells. Here, we aim to bioprint and mineralize cell-laden gelatin methacrylate (GelMA) microgels and test the effects of cryopreservation on cell viability for bone tissue engineering applications.
000009584 540__ $$fCC BY
000009584 542__ $$fIn copyright - joint owners
000009584 650__ $$aBioprinting$$040002
000009584 650__ $$aBone Regeneration$$015733
000009584 650__ $$aMicrogels$$013109
000009584 650__ $$aOsteocytes$$023346
000009584 6531_ $$amineralization
000009584 6531_ $$abone grafting
000009584 6531_ $$aautograft
000009584 7001_ $$aSousa, Mauricio$$uOregon Health and Science University$$041354
000009584 7001_ $$aBalbinot, Gabriela$$uOregon Health and Science University$$041354
000009584 7001_ $$aVisalakshan, Rauhl$$uOregon Health and Science University$$041354
000009584 7001_ $$aSubiah, Ramesh$$uOregon Health and Science University$$041354
000009584 7001_ $$aBertassoni, Luiz$$uOregon Health and Science University$$041354
000009584 711__ $$aResearch Week$$uOregon Health and Science University$$d2022
000009584 8564_ $$95a6d4253-cac6-4502-b7dc-fa65c1a0326e$$s172079$$uhttps://digitalcollections.ohsu.edu/record/9584/files/Sousa-Mauricio-OHSU-ResearchWeek-2022.pdf
000009584 905__ $$a/rest/prod/86/23/hz/55/8623hz558
000009584 980__ $$aResearch Week