000009596 001__ 9596 000009596 005__ 20240404153107.0 000009596 0247_ $$2DOI$$a10.6083/h128nf502 000009596 037__ $$aIR 000009596 041__ $$aeng 000009596 245__ $$aEffect of hepatic arterial infusion pumps on PET/MR images 000009596 260__ $$bOregon Health and Science University 000009596 269__ $$a2022 000009596 336__ $$aAbstract 000009596 520__ $$aAttenuation correction (AC) in PET/MR imaging significantly alters the displayed PET signal. Modern AC methods forgo the process of directly calculating attenuation through transmission scans by using MR data to assign a tissue class and corresponding attenuation value to each voxel. However, MR AC often fails in the vicinity of medical implants, which create artifacts in the MR signal. Artifacts cause misclassification of tissue in the AC map, leading to miscalculation of PET signal. These issues are anticipated to affect PET/MR images of colorectal cancer patients with hepatic arterial infusion pumps (HAIPs). However, PET/MR imaging of these patients is desired for simultaneous visualization of liver soft tissue contrast and PET tracer uptake. This research investigated the effect of HAIPs on PET signal using various AC methods. 000009596 540__ $$fCC BY 000009596 542__ $$fIn copyright - joint owners 000009596 650__ $$aDiagnostic Imaging$$017700 000009596 650__ $$aImage Processing, Computer-Assisted$$020650 000009596 650__ $$aDrug Therapy$$018086 000009596 650__ $$aColorectal Neoplasms$$028197 000009596 650__ $$aPositron Emission Tomography Computed Tomography$$011903 000009596 650__ $$aMagnetic Resonance Imaging, Interventional$$037612 000009596 650__ $$aPhantoms, Imaging$$031310 000009596 6531_ $$ahepatic arterial infusion pump 000009596 6531_ $$acolorectal cancer 000009596 6531_ $$amedical physics 000009596 6531_ $$achemotherapy 000009596 6531_ $$aattenuation correction 000009596 6531_ $$aliver metastasis 000009596 7001_ $$aWishart, Joseph$$uOregon Health and Science University$$041354 000009596 7001_ $$aWinters, Celeste$$uOregon Health and Science University$$041354 000009596 7001_ $$aMench, Anna$$uOregon Health and Science University$$041354 000009596 7001_ $$aGillan, Derrick$$uOregon Health and Science University$$041354 000009596 711__ $$aResearch Week$$uOregon Health and Science University$$d2022 000009596 8564_ $$9b9ff3c94-a7e5-4fee-ae6f-4fdb9cb29ce7$$s160511$$uhttps://digitalcollections.ohsu.edu/record/9596/files/Wishart-Joseph-OHSU-ResearchWeek-2022.pdf 000009596 905__ $$a/rest/prod/h1/28/nf/50/h128nf502 000009596 980__ $$aResearch Week