TY  - GEN
N2  - Amyloid beta (A?) plaques represent one of the classic hallmarks of Alzheimer's disease (AD) pathology in the brain. In rhesus macaques, these plaques start becoming prominent when the animals are 20+ years old, although the underlying cause(s) are unclear. In the present study, our goal was to test the hypothesis that exposure to a Western-style, high-fat, high-sugar diet (WSD) and/or loss of ovarian steroids would advance the development of this histological marker of AD pathology.
DO  - 10.6083/0k225b88q
DO  - DOI
AB  - Amyloid beta (A?) plaques represent one of the classic hallmarks of Alzheimer's disease (AD) pathology in the brain. In rhesus macaques, these plaques start becoming prominent when the animals are 20+ years old, although the underlying cause(s) are unclear. In the present study, our goal was to test the hypothesis that exposure to a Western-style, high-fat, high-sugar diet (WSD) and/or loss of ovarian steroids would advance the development of this histological marker of AD pathology.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Effect of hormone replacement therapy on amyloid beta expression in the amygdala of aged Rhesus Macaques
DA  - 2022-04-13
AU  - Appleman, Maria-Luisa
AU  - Nilaver, Benjamin
AU  - Kohama, Steven G.
AU  - Urbanski, Henryk F.
L1  - https://digitalcollections.ohsu.edu/record/9601/files/ResearchWeek2022-Abstract_Luisa_Appleman.pdf
PB  - Oregon Health and Science University
LA  - eng
PY  - 2022-04-13
ID  - 9601
L4  - https://digitalcollections.ohsu.edu/record/9601/files/ResearchWeek2022-Abstract_Luisa_Appleman.pdf
KW  - Amyloid
KW  - Amygdala
KW  - Hormone Replacement Therapy
KW  - Dementia
KW  - Alzheimer Disease
KW  - Estrogens
KW  - Macaca mulatta
KW  - rhesus macaque
TI  - Effect of hormone replacement therapy on amyloid beta expression in the amygdala of aged Rhesus Macaques
Y1  - 2022-04-13
L2  - https://digitalcollections.ohsu.edu/record/9601/files/ResearchWeek2022-Abstract_Luisa_Appleman.pdf
LK  - https://digitalcollections.ohsu.edu/record/9601/files/ResearchWeek2022-Abstract_Luisa_Appleman.pdf
UR  - https://digitalcollections.ohsu.edu/record/9601/files/ResearchWeek2022-Abstract_Luisa_Appleman.pdf
ER  -