TY - GEN N2 - Rod bipolar cells (RBCs) are the first interneurons in the primary rod visual pathway. RBCs transmit light-driven signals from rods in the outer retina and contribute to retinal output through downstream amacrine cells (ACs) in the inner retina. This thesis presents my work identifying and characterizing trophoblast glycoprotein (TPBG), a leucine-rich repeat transmembrane protein recently identified in RBCs. Similar leucine-rich repeat proteins in RBCs are essential for synaptic targeting, correct localization of signal transduction proteins, and regulating the RBC light response across different light intensities DO - 10.6083/2r36tz28b DO - DOI AB - Rod bipolar cells (RBCs) are the first interneurons in the primary rod visual pathway. RBCs transmit light-driven signals from rods in the outer retina and contribute to retinal output through downstream amacrine cells (ACs) in the inner retina. This thesis presents my work identifying and characterizing trophoblast glycoprotein (TPBG), a leucine-rich repeat transmembrane protein recently identified in RBCs. Similar leucine-rich repeat proteins in RBCs are essential for synaptic targeting, correct localization of signal transduction proteins, and regulating the RBC light response across different light intensities T1 - Characterization of trophoblast glycoprotein in retinal rod bipolar cells DA - 2022 AU - Wakeham, Colin L1 - https://digitalcollections.ohsu.edu/record/9605/files/Wakeham.Colin.2022.pdf PB - Oregon Health and Science University PY - 2022 ID - 9605 L4 - https://digitalcollections.ohsu.edu/record/9605/files/Wakeham.Colin.2022.pdf KW - Neurobiology KW - Retina KW - phosphoproteomics KW - protein kinase c alpha KW - amacrine cell KW - rod bipolar cell TI - Characterization of trophoblast glycoprotein in retinal rod bipolar cells Y1 - 2022 L2 - https://digitalcollections.ohsu.edu/record/9605/files/Wakeham.Colin.2022.pdf LK - https://digitalcollections.ohsu.edu/record/9605/files/Wakeham.Colin.2022.pdf UR - https://digitalcollections.ohsu.edu/record/9605/files/Wakeham.Colin.2022.pdf ER -