000009605 001__ 9605
000009605 005__ 20240124114325.0
000009605 0247_ $$2DOI$$a10.6083/2r36tz28b
000009605 037__ $$aETD
000009605 245__ $$aCharacterization of trophoblast glycoprotein in retinal rod bipolar cells
000009605 260__ $$bOregon Health and Science University
000009605 269__ $$a2022
000009605 336__ $$aDissertation
000009605 502__ $$bPh.D.
000009605 520__ $$aRod bipolar cells (RBCs) are the first interneurons in the primary rod visual pathway. RBCs transmit light-driven signals from rods in the outer retina and contribute to retinal output through downstream amacrine cells (ACs) in the inner retina. This thesis presents my work identifying and characterizing trophoblast glycoprotein (TPBG), a leucine-rich repeat transmembrane protein recently identified in RBCs. Similar leucine-rich repeat proteins in RBCs are essential for synaptic targeting, correct localization of signal transduction proteins, and regulating the RBC light response across different light intensities
000009605 542__ $$fIn copyright - single owner
000009605 650__ $$aNeurobiology$$022831
000009605 650__ $$aRetina$$025387
000009605 6531_ $$aphosphoproteomics
000009605 6531_ $$aprotein kinase c alpha
000009605 6531_ $$aamacrine cell
000009605 6531_ $$arod bipolar cell
000009605 691__ $$aSchool of Medicine$$041369
000009605 7001_ $$aWakeham, Colin
000009605 8564_ $$9b62a8606-109d-4029-a585-73cde245f083$$s10845948$$uhttps://digitalcollections.ohsu.edu/record/9605/files/Wakeham.Colin.2022.pdf
000009605 905__ $$a/rest/prod/2r/36/tz/28/2r36tz28b
000009605 909CO $$ooai:digitalcollections.ohsu.edu:9605$$pstudent-work
000009605 980__ $$aTheses and Dissertations