TY  - GEN
N2  - IgA Vasculitis (IgAV) is a systemic small vessel vasculitis that affects the skin, joints, gastrointestinal tract, and kidneys. IgAV is the one of the most common glomerulonephritides in children, yet it is rare in adults and is associated with a worse prognosis. Though histologically similar to Immunoglobuin A Nephropathy (IgAN), IgAV is a systemic disease that has a unique clinical course. A few large retrospective trials in adults have shown that IgAV patients with a greater degree of proteinuria, kidney insufficiency at time of biopsy, and hypertension have worse overall prognosis and that ?/? of these patients develop progressive kidney disease. A scoring index known as the Oxford Classication (MEST-C classification) has been used to prognose patients with IgAN. Retrospective cohort studies in European and Asian populations have evaluated the prognostic capabilities of the Oxford classification for IgAV and have had varying results. The goal of this study is to explore clinical and histologic prognostic factors (using the Oxford Classification) that predispose IgAV patients to progressive kidney disease. We also hope to compile and analyze treatment data. Identification of factors that are predictive of poor outcomes will improve patient treatment plans and education.
DO  - 10.6083/s1784m488
DO  - DOI
AB  - IgA Vasculitis (IgAV) is a systemic small vessel vasculitis that affects the skin, joints, gastrointestinal tract, and kidneys. IgAV is the one of the most common glomerulonephritides in children, yet it is rare in adults and is associated with a worse prognosis. Though histologically similar to Immunoglobuin A Nephropathy (IgAN), IgAV is a systemic disease that has a unique clinical course. A few large retrospective trials in adults have shown that IgAV patients with a greater degree of proteinuria, kidney insufficiency at time of biopsy, and hypertension have worse overall prognosis and that ?/? of these patients develop progressive kidney disease. A scoring index known as the Oxford Classication (MEST-C classification) has been used to prognose patients with IgAN. Retrospective cohort studies in European and Asian populations have evaluated the prognostic capabilities of the Oxford classification for IgAV and have had varying results. The goal of this study is to explore clinical and histologic prognostic factors (using the Oxford Classification) that predispose IgAV patients to progressive kidney disease. We also hope to compile and analyze treatment data. Identification of factors that are predictive of poor outcomes will improve patient treatment plans and education.
AD  - Oregon Health and Science University
AD  - Oregon Health and Science University
T1  - Clinical & histologic predictors of IgA vasculitis in adults
ED  - Avasare, Rupali
ED  - Mentor
DA  - 2022
AU  - Meenakshi, Vanka
AU  - Kim, Taesoo
L1  - https://digitalcollections.ohsu.edu/record/9627/files/Vanka.Meenakshi.2022.pdf
PB  - Oregon Health and Science University
PY  - 2022
ID  - 9627
L4  - https://digitalcollections.ohsu.edu/record/9627/files/Vanka.Meenakshi.2022.pdf
KW  - IgA Vasculitis
KW  - oxford classification
TI  - Clinical & histologic predictors of IgA vasculitis in adults
Y1  - 2022
L2  - https://digitalcollections.ohsu.edu/record/9627/files/Vanka.Meenakshi.2022.pdf
LK  - https://digitalcollections.ohsu.edu/record/9627/files/Vanka.Meenakshi.2022.pdf
UR  - https://digitalcollections.ohsu.edu/record/9627/files/Vanka.Meenakshi.2022.pdf
ER  -