000009627 001__ 9627
000009627 005__ 20240125143601.0
000009627 0247_ $$2DOI$$a10.6083/s1784m488
000009627 037__ $$aIR
000009627 245__ $$aClinical & histologic predictors of IgA vasculitis in adults
000009627 260__ $$bOregon Health and Science University
000009627 269__ $$a2022
000009627 336__ $$aCapstone
000009627 502__ $$gMedicine (Undergraduate Medical Education)
000009627 502__ $$bM.D.
000009627 520__ $$aIgA Vasculitis (IgAV) is a systemic small vessel vasculitis that affects the skin, joints, gastrointestinal tract, and kidneys. IgAV is the one of the most common glomerulonephritides in children, yet it is rare in adults and is associated with a worse prognosis. Though histologically similar to Immunoglobuin A Nephropathy (IgAN), IgAV is a systemic disease that has a unique clinical course. A few large retrospective trials in adults have shown that IgAV patients with a greater degree of proteinuria, kidney insufficiency at time of biopsy, and hypertension have worse overall prognosis and that ?/? of these patients develop progressive kidney disease. A scoring index known as the Oxford Classication (MEST-C classification) has been used to prognose patients with IgAN. Retrospective cohort studies in European and Asian populations have evaluated the prognostic capabilities of the Oxford classification for IgAV and have had varying results. The goal of this study is to explore clinical and histologic prognostic factors (using the Oxford Classification) that predispose IgAV patients to progressive kidney disease. We also hope to compile and analyze treatment data. Identification of factors that are predictive of poor outcomes will improve patient treatment plans and education.
000009627 650__ $$aIgA Vasculitis$$024944
000009627 6531_ $$aoxford classification
000009627 7001_ $$aMeenakshi, Vanka$$uOregon Health and Science University$$041354
000009627 7001_ $$aKim, Taesoo$$uOregon Health and Science University$$041354
000009627 7201_ $$aAvasare, Rupali$$uOregon Health and Science University$$041354$$7Personal$$eMentor
000009627 8564_ $$99a775b48-1d0d-49a4-b5b1-a1bc6f131043$$s900702$$uhttps://digitalcollections.ohsu.edu/record/9627/files/Vanka.Meenakshi.2022.pdf
000009627 905__ $$a/rest/prod/s1/78/4m/48/s1784m488
000009627 909CO $$ooai:digitalcollections.ohsu.edu:9627$$pstudent-work
000009627 980__ $$aScholarly Project Capstones