@article{ETD,
      school = {Ph.D.},
      author = {Blake, Matthew R.},
      url = {http://digitalcollections.ohsu.edu/record/9690},
      title = {Chondroitin sulfate proteoglycan sulfation patterns  prevent sympathetic nerve regeneration after myocardial  infarction},
      publisher = {Oregon Health and Science University},
      abstract = {Sympathetic nerves are lost in the damaged myocardium  (infarct) after myocardial infarction (MI), and the  relative area of denervation predicts risk of sudden  cardiac arrest due to arrhythmias leading to the hypothesis  that sympathetic reinnervation of the infarct could reduce  arrhythmias. This dissertation also describes an attempt to  use genetically encoded FRET-biosensors to understand  signaling pathways downstream ofTrkA altered by CSPGs. Due  to a number of technological challenges, we limited our  assessment to Protein Kinase A (PKA) and Protein Kinase C  (PKC) sensors in primary sympathetic neurons but we did not  observe any significant responses to CSPGs.},
      number = {ETD},
      doi = {https://doi.org/10.6083/5425kb45p},
      recid = {9690},
      address = {2022},
}