TY  - GEN
AB  - This dissertation focuses on brain aging and neurodegeneration, specifically in the context of healthy brain aging versus Alzheimer's disease (AD). To study these processes, a translational model of human aging is necessitated; therefore, this dissertation will focus on the rhesus macaque's utility in modeling clinically normative and pathological brain aging. Protein-level consequences of central nervous system (CNS) aging in monkeys will be experimentally explored and discussed in comparison to concomitant clinical phenotypes.
AU  - Stonebarger, Gail
DA  - 2022
DO  - 10.6083/zs25x9220
DO  - DOI
ID  - 9751
KW  - Amyloid beta-Peptides
KW  - Macaca mulatta
KW  - Alzheimer Disease
KW  - Caloric Restriction
KW  - Aging
KW  - Biomarkers
L1  - https://digitalcollections.ohsu.edu/record/9751/files/Stonebarger.Gail.2022.pdf
L2  - https://digitalcollections.ohsu.edu/record/9751/files/Stonebarger.Gail.2022.pdf
L4  - https://digitalcollections.ohsu.edu/record/9751/files/Stonebarger.Gail.2022.pdf
LK  - https://digitalcollections.ohsu.edu/record/9751/files/Stonebarger.Gail.2022.pdf
N2  - This dissertation focuses on brain aging and neurodegeneration, specifically in the context of healthy brain aging versus Alzheimer's disease (AD). To study these processes, a translational model of human aging is necessitated; therefore, this dissertation will focus on the rhesus macaque's utility in modeling clinically normative and pathological brain aging. Protein-level consequences of central nervous system (CNS) aging in monkeys will be experimentally explored and discussed in comparison to concomitant clinical phenotypes.
PB  - Oregon Health and Science University
PY  - 2022
T1  - A clinically driven characterization of pathological and non-pathological brain aging in the Rhesus Macaque model: impact of caloric restriction
TI  - A clinically driven characterization of pathological and non-pathological brain aging in the Rhesus Macaque model: impact of caloric restriction
UR  - https://digitalcollections.ohsu.edu/record/9751/files/Stonebarger.Gail.2022.pdf
Y1  - 2022
ER  -