@article{ETD,
      school = {Ph.D.},
      author = {Bouchet, Courtney A.},
      url = {http://digitalcollections.ohsu.edu/record/9759},
      title = {Persistent inflammation desensitizes the presynaptic  cannabinoid CB1 receptor},
      publisher = {Oregon Health and Science University},
      abstract = {The majority of pharmaceutical drugs on the market target  G protein coupled receptor (GPCRs); however, GPCR signaling  and regulation adapt in response to environmental stimuli.  One GPCR gaining attention due to the increasing  legalization of cannabis is the cannabinoid 1 receptor  (CB1R). Cannabis legalization is leading to increased use  to treat pain and other ailments, including pain caused by  inflammation. Studies presented throughout this  dissertation investigate adaptations in synaptic CB1R  suppression of GABA release after persistent inflammation  induced by Complete Freund?s Adjuvant (CFA).},
      number = {ETD},
      doi = {https://doi.org/10.6083/8336h2599},
      recid = {9759},
      address = {2022},
}