TY - THES N2 - The greatest risk factor for developing Parkinson's disease is aging, and the accumulation of reactive oxygen species is thought to play a significant role in the aging process. Glutathione is a universal antioxidant in animals and plants that helps maintain redox homeostasis within cells, preventing or delaying excessive buildup of reactive oxygen species that may damage or destroy the cell. The work presented in this thesis adds to our understanding of how glutathione affects the aging process and its therapeutic potential in aging-related neurodegenerative diseases like Parkinson's disease. DO - 10.6083/5999n428r DO - DOI AB - The greatest risk factor for developing Parkinson's disease is aging, and the accumulation of reactive oxygen species is thought to play a significant role in the aging process. Glutathione is a universal antioxidant in animals and plants that helps maintain redox homeostasis within cells, preventing or delaying excessive buildup of reactive oxygen species that may damage or destroy the cell. The work presented in this thesis adds to our understanding of how glutathione affects the aging process and its therapeutic potential in aging-related neurodegenerative diseases like Parkinson's disease. T1 - Investigating the role of glutathione in Drosophila lifespan and neuronal health DA - 2022 AU - Coleman, Colin L1 - https://digitalcollections.ohsu.edu/record/9958/files/Coleman.Colin.2022.pdf PB - Oregon Health and Science University PY - 2022 ID - 9958 L4 - https://digitalcollections.ohsu.edu/record/9958/files/Coleman.Colin.2022.pdf KW - Antioxidants KW - Longevity KW - Aging KW - Neurosciences KW - Drosophila melanogaster KW - Oxidative Stress TI - Investigating the role of glutathione in Drosophila lifespan and neuronal health Y1 - 2022 L2 - https://digitalcollections.ohsu.edu/record/9958/files/Coleman.Colin.2022.pdf LK - https://digitalcollections.ohsu.edu/record/9958/files/Coleman.Colin.2022.pdf UR - https://digitalcollections.ohsu.edu/record/9958/files/Coleman.Colin.2022.pdf ER -