TY  - GEN
AB  - During development, cells must migrate from their origin to their final destination, a process that is dependent on the actin cytoskeleton. Cells can migrate independently or cohesively as a unit, in a process known as collective cell migration. In migrating cells, the actin cytoskeleton facilitates migration through the extension of actin-based protrusions, promoting adherence to the extracellular environment, and the retraction of trailing portions of cells. The regulation of these actin-based cellular mechanisms has been heavily studied in populations of individually migrating cells, mostly in in vitro contexts. However, how these processes are regulated and coordinated during collective cell migration in vivo remains largely unknown.
AU  - Olson, Hannah M.
DA  - 2022
DO  - 10.6083/k930bx65n
DO  - DOI
ID  - 9965
KW  - Cell Movement
KW  - Constriction
KW  - Zebrafish
KW  - Developmental Biology
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N2  - During development, cells must migrate from their origin to their final destination, a process that is dependent on the actin cytoskeleton. Cells can migrate independently or cohesively as a unit, in a process known as collective cell migration. In migrating cells, the actin cytoskeleton facilitates migration through the extension of actin-based protrusions, promoting adherence to the extracellular environment, and the retraction of trailing portions of cells. The regulation of these actin-based cellular mechanisms has been heavily studied in populations of individually migrating cells, mostly in in vitro contexts. However, how these processes are regulated and coordinated during collective cell migration in vivo remains largely unknown.
PB  - Oregon Health and Science University
PY  - 2022
T1  - Regulation of cytoskeletal dynamics promotes proper collective cell migration
TI  - Regulation of cytoskeletal dynamics promotes proper collective cell migration
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Y1  - 2022
ER  -