TY - GEN AB - Optical coherence tomographic angiography (OCTA) has been successfully used in ophthalmol-ogy, providing noninvasive, non-dye-based, high-speed, and depth-resolved imaging of retinal and choroidal circulatory networks in vivo at capillary-scale detail. OCTA is able to detect capillary dropout and nonexudative choroidal neovascularization (CNV), which may be missed by traditional imaging modalities such as fluorescein angiograph (FA) / indocyanine green angiograph (ICGA), and are risk factors for vision loss. This dissertation presents technical achievements in plexus-specific micro-vascular disorder detection on OCTA, including (i) projection artifacts removal, (ii) macular ischemia detection in vascular layers in the inner retina, (iii) CNV detection in the outer retina, and (iv) wide-field OCTA generated by stitching miltiple small-field OCTA seamlessly. AU - Wang, Jie DA - 2022 DO - 10.6083/0k225b929 DO - DOI ID - 9973 KW - Angiography KW - Choroidal Neovascularization KW - Deep Learning L1 - https://digitalcollections.ohsu.edu/record/9973/files/Wang.Jie.2022.pdf L2 - https://digitalcollections.ohsu.edu/record/9973/files/Wang.Jie.2022.pdf L4 - https://digitalcollections.ohsu.edu/record/9973/files/Wang.Jie.2022.pdf LK - https://digitalcollections.ohsu.edu/record/9973/files/Wang.Jie.2022.pdf N2 - Optical coherence tomographic angiography (OCTA) has been successfully used in ophthalmol-ogy, providing noninvasive, non-dye-based, high-speed, and depth-resolved imaging of retinal and choroidal circulatory networks in vivo at capillary-scale detail. OCTA is able to detect capillary dropout and nonexudative choroidal neovascularization (CNV), which may be missed by traditional imaging modalities such as fluorescein angiograph (FA) / indocyanine green angiograph (ICGA), and are risk factors for vision loss. This dissertation presents technical achievements in plexus-specific micro-vascular disorder detection on OCTA, including (i) projection artifacts removal, (ii) macular ischemia detection in vascular layers in the inner retina, (iii) CNV detection in the outer retina, and (iv) wide-field OCTA generated by stitching miltiple small-field OCTA seamlessly. PB - Oregon Health and Science University PY - 2022 T1 - Plexus-specific micro-vascular pathologies defined by optical coherence tomographic angiography TI - Plexus-specific micro-vascular pathologies defined by optical coherence tomographic angiography UR - https://digitalcollections.ohsu.edu/record/9973/files/Wang.Jie.2022.pdf Y1 - 2022 ER -