000009973 001__ 9973
000009973 005__ 20231129124952.0
000009973 0247_ $$2DOI$$a10.6083/0k225b929
000009973 037__ $$aETD
000009973 245__ $$aPlexus-specific micro-vascular pathologies defined by optical coherence tomographic angiography
000009973 260__ $$bOregon Health and Science University
000009973 269__ $$a2022
000009973 336__ $$aDissertation
000009973 502__ $$bPh.D.
000009973 520__ $$aOptical coherence tomographic angiography (OCTA) has been successfully used in ophthalmol-ogy, providing noninvasive, non-dye-based, high-speed, and depth-resolved imaging of retinal and choroidal circulatory networks in vivo at capillary-scale detail. OCTA is able to detect capillary dropout and nonexudative choroidal neovascularization (CNV), which may be missed by traditional imaging modalities such as fluorescein angiograph (FA) / indocyanine green angiograph (ICGA), and are risk factors for vision loss. This dissertation presents technical achievements in plexus-specific micro-vascular disorder detection on OCTA, including (i) projection artifacts removal, (ii) macular ischemia detection in vascular layers in the inner retina, (iii) CNV detection in the outer retina, and (iv) wide-field OCTA generated by stitching miltiple small-field OCTA seamlessly.
000009973 542__ $$fIn copyright - single owner
000009973 650__ $$aAngiography$$014747
000009973 650__ $$aChoroidal Neovascularization$$032269
000009973 650__ $$aDeep Learning$$012734
000009973 691__ $$aSchool of Medicine$$041369
000009973 692__ $$aDepartment of Biomedical Engineering$$041397
000009973 7001_ $$aWang, Jie
000009973 8564_ $$9f7542f51-1e76-4b30-a82a-cd295bbdd9c6$$s74813019$$uhttps://digitalcollections.ohsu.edu/record/9973/files/Wang.Jie.2022.pdf
000009973 905__ $$a/rest/prod/0k/22/5b/92/0k225b929
000009973 909CO $$ooai:digitalcollections.ohsu.edu:9973$$pstudent-work
000009973 980__ $$aTheses and Dissertations