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1.	PDF Novel models and methods for the functional characterization of disease relevant SDHA variants Kent, Jason ; Heinrich, Michael ; Agarwal, Anupriya ; McCullough, Amanda[...] Individuals who inherit a pathogenic mutation in SDHA have an increased risk of cancer. However, there is often insufficient evidence to properly assess pathogenicity, an [...] 2023-12-14 \| Dissertation \| Detailed record - Similar records
2.	PDF Kent-Jason-OHSU-ResearchWeek-2022 Novel SDHA-knockout cell line enables sensitive functional characterization of SDHA VUS Kent, Jason D. ; Heinrich, Michael C. Genetic inactivation of SDHA can lead to succinate dehydrogenase (SDH)-deficiency and is implicated in a variety of human diseases. In particular, germline loss-of-functi [...] 2022 \| Abstract \| Detailed record - Similar records
3.	PDF Khosroyani-Homma-OHSU-ResearchWeek-2022 Predicting Imatinib responses in exon 18 PDGFRA-mutant GIST Khosroyani, Homma M. ; Heinrich, Michael C. The majority of gastrointestinal stromal tumor (GIST) are driven by mutations in KIT or platelet derived growth factor receptor alpha (PDGFRA) receptor tyrosine kinases. [...] 2022 \| Abstract \| Detailed record - Similar records
4.	PDF Khosroyani-Homma-OHSU-ResearchWeek-2021 Primary Imatinib resistance in PDGFRA-mutant GIST Khosroyani, Homma M. ; Klug, Lillian ; Heinrich, Michael Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the GI tract. The second most common type of GIST is driven by oncogenic mutations in PDGFRA, of which [...] 2021 \| Abstract \| Detailed record - Similar records

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