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OHSU 2 records found Search took 0.50 seconds. 
1.
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Sharzehi-Setareh-OHSU-ResearchWeek-2022
The FLT3 F691L gatekeeper mutation promotes clinical resistance to Gilteritinib + Venetoclax in AML
Sharzehi, Setareh ; Joshi, Sunil ; Pittsenbarger, Janet ; Bottomly, Daniel[...]
Acute Myeloid Leukemia (AML) is an aggressive cancer with poor overall survival due to frequent relapse. FMS-like tyrosine kinase (FLT3) is the most commonly mutated gene [...]
2022 | Abstract |
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2.
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Novel models and methods for the functional characterization of disease relevant SDHA variants
Kent, Jason ; Heinrich, Michael ; Agarwal, Anupriya ; McCullough, Amanda[...]
Individuals who inherit a pathogenic mutation in SDHA have an increased risk of cancer. However, there is often insufficient evidence to properly assess pathogenicity, an [...]
2023-12-14 | Dissertation |
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