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> Search Results: ( (keyword:"tnk2 protein"))
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Publication Type
Dissertation (1)
Year
2017 (1)
Topic
Dasatinib (1)
Leukemia (1)
Mitogen-Activated Protein Kinases (1)
Name
Jenkins, Chelsea (1)
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Theses and Dissertations (1)
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Dissertation (1)
Year
2017 (1)
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Dasatinib (1)
Leukemia (1)
Mitogen-Activated Protein Kinases (1)
Name
Jenkins, Chelsea (1)
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Theses and Dissertations (1)
OHSU
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Jenkins.Chelsea.2017
Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia
Jenkins, Chelsea
This dissertation presents novel evidence that PTPN11 is activated by an upstream kinase, TNK2. PTPN11-mutant JMML and AML primary patient cells have displayed significan [...]
2017
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