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Super resolution microscopy (SRM) comprises various single-molecule localization techniques that can generate images at the 20 nm scale. In recent years, SRM based on DNA [...]
2020 |
Abstract |
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3.
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Successful cancer treatment continues to elude modern medicine and its arsenal of therapeutic strategies. Therapy resistance is driven by tumor heterogeneity, complex int [...]
2020 |
Abstract |
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Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide, with high morbidity, high mortality, and few therapeutic options outside of surgery [...]
2017 |
Dissertation |
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Certain cancers, including gastrointestinal stromal tumor (GIST) and subsets of melanoma, are caused by somatic KIT mutations that result in constitutive KIT receptor tyr [...]
2017 |
Dissertation |
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The majority of gastrointestinal stromal tumor (GIST) are driven by mutations in KIT or platelet derived growth factor receptor alpha (PDGFRA) receptor tyrosine kinases. [...]
2022 |
Abstract |
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This thesis work focuses on technical developments in the field of superresolution fluorescence microscopy (SRM) and applications of SRM to probing the spatial organizati [...]
2017 |
Dissertation |
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9.
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This thesis describes the role of RI-I modulation in the vascular system. I identify a novel role for RIG-I activation in endothelial function, as well as a role for RIG- [...]
2024-02-07 |
Dissertation |
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10.
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