A dissertation with a central goal of elucidating to what extent emotion regulation, measured behaviorally and neurobiologically, can explain the association between NLEs [...]

This dissertation investigates the dynamics of intracellular signaling cascades as a functional readout of neuromodulation. Specifically, newly developed fluorescence lif [...]

Adolescent social isolation is a developmental stressor that increases vulnerability to neuropsychiatric disorders including substance use disorder and eating disorders. [...]

Binge drinking is associated with the genetic risk of developing alcohol use disorder (AUD) and is considered a strong predictor of AUD diagnosis. Excessive alcohol drin [...]

The goal of this dissertation was to understand if sex-specific responses to NAcC chemogenetic manipulations indicate differences in reward, or NAcC input and brain regio [...]

This dissertation examines how TAAR1 functionality influences dorsal raphe serotonin neuron activity, glutamatergic inputs, and methamphetamine (MA) intake in mice with d [...]

The brain regulates nociceptive processing through descending projections from the brainstem to the spinal and trigeminal dorsal horns. This is accomplished through endog [...]

The nucleus accumbens plays a key role in guiding motivated behavior by integrating glutamate inputs, the major driver of neuronal activation, and dopamine (DA) inputs, a [...]

Psychosis is a hallmark of schizophrenia. It typically emerges in late adolescence and is associated with striatal dopamine abnormalities. Most genes implicated in the ri [...]

The etiology of adolescent internalizing psychopathology (e.g., anxiety and depression) is not yet fully understood, and for that reason it has been difficult to identify [...]