Biomedical Engineering

The musculoskeletal system includes important structures like muscles and bones that help us move. While minor injuries often heal fully, serious damage can lead to long- [...]

Cell-cell co-occurrence patterns are critical in shaping biological and clinical phenotypes, but existing tools for analyzing single-cell RNA sequencing (scRNA-seq) data [...]

This thesis presents a suite of deep learning frameworks designed to address key challenges in the analysis of Electron Microscopy (EM) images of cancer cells, which are [...]

This dissertation aims to present technological and therapeutic innovations to meet clinical needs in the field of cancer detection and treatment. The presented work rev [...]

Tumors overexpressing the HER2 oncogene account for around 20% of breast cancer cases and are associated with aggressive disease. These tumors generally originate from a [...]

Triple Negative Breast Cancer (TNBC) is a complex malignancy subtype which commonly forms aggressive tumors with substantial stromal involvement. Unlike the Luminal and H [...]

Pathological thrombosis is a significant driver of human morbidity and mortality today. Overall, this dissertation presents a study of the pathophysiology, clinical manag [...]

This dissertation focuses on developing advanced handheld OCT and OCTA systems tailored for pediatric use, overcoming the limitations of traditional and commercially avai [...]

Interferon regulatory factor 6 plays a significant role in the regulation of intestinal epithelial cell identity, interferon response, and apoptosis.

Cachexia and cancer, when intertwined, precipitate severe adverse outcomes for patients, underscoring the urgent need for innovative therapeutic strategies. This disserta [...]