This dissertation addresses the urgent clinical need to develop and identify blood-based biomarkers for cancer that can help avoid unnecessary surgeries for benign masses [...]

This dissertation develops physiology-guided machine learning digital twins and a person-centered decision support system to improve personalized diabetes management. By [...]

Most patients with solid tumors do not respond to immune checkpoint blockade, often because their tumors lack sufficient cytotoxic CD8+ T cells. Interleukin-2 (IL-2) can [...]

Myelination depends on oligodendrocyte lineage cells (OLCs) accurately sensing and responding to physical cues within the central nervous system. This work identifies the [...]

This dissertation investigates why remyelination becomes inefficient with age in multiple sclerosis (MS) and how this failure drives neuronal loss. Key findings include a [...]

This dissertation examined latent subgroups of adverse childhood experiences among healthcare professionals in Oregon and whether subgroup membership was associated with [...]

This dissertation aims to discover potential explanations for nursing's lack of engagement with prison abolition by examining nurses' discussions of prison abolition and [...]

Diversification of social identities and demographic categories in nursing remains stagnant despite its importance to addressing health inequality. Inclusive work environ [...]

This dissertation presents three interlocking empirical studies united by a single dynamical systems framework: that behavioral flexibility depends on the moment-to-momen [...]

The chapters of this dissertation focus on understanding the mechanisms by which different CSF3R mutations identified in CNL drive leukemic transformation, with the ultim [...]