Doctor of Philosophy (Ph.D.)

Zoonoses— infectious diseases transmitted between animals and humans—inflict a heavy toll on the economy, health, and livelihood worldwide. One Health serves as a framewo [...]

This dissertation investigates the role of weaning-induced liver tissue remodeling, known as involution, on stromal cells in the liver. We transcriptionally investigate c [...]

The structural and functional characterization of the human bile acid ion channel in the presence and absence of calcium are discussed.

Pioneer neurons establish the initial nervous system structure by extending axons toward distant targets, but their molecular distinction from follower neurons was previo [...]

The goal of this dissertation is to improve our understanding of the factors governing genetic repair to facilitate whole gene insertion into the genome of mature organis [...]

This dissertation investigates the molecular link between Parkinson's Disease and melanoma. Specifically, this work presents novel findings showing that alpha-synuclein f [...]

The musculoskeletal system includes important structures like muscles and bones that help us move. While minor injuries often heal fully, serious damage can lead to long- [...]

A dissertation discussing the role of mesenchymal kit ligand (kitl) in the pancreas, specifically in regards to healthy tissue homeostasis, tissue architecture, and disea [...]

ADP-ribosylation is a dynamic post-translational modification predominantly catalyzed by a large family of enzymes called PARPs. PARPs are implicated in diseases such as [...]

My work resulted in the discovery of a novel KATP channel pharmacochaperone, Aekatperone, through AI-driven virtual screening of the drug binding site using the Cryo-EM s [...]