Oregon National Primate Research Center

Intrauterine infection is associated with preterm labor and perinatal brain injury. Choriodecidual infection represents an early stage of ascending reproductive infection [...]

The use of multimodal analgesia is preferred over single-agent analgesia for postoperative pain management due to synergistic modulations of pain pathways. The two most c [...]

Pregnancy causes complex hormonal changes, leading to physiologic decreases of insulin sensitivity, onset of gestational diabetes (GDM), and worsening conditions associat [...]

Roux-en-Y gastric bypass (RYGB) alters the stomach and intestine in ways that reduce caloric intake and absorption. These changes can also decrease absorption of nutrient [...]

Fetal sex determination (FSD) is a cell-free DNA (cfDNA) screening assay that determines the presence of sex-linked fetal malformations using maternal serum or plasma. FS [...]

HIV/AIDS is a chronic disease that causes increased inflammation and decreased immune function within people living with HIV (PLWH). A majority of PLWH are women; however [...]

Access to early gestational placental tissue in humans is constrained by a host of ethical challenges. As a result, early events of placentation and fetal development are [...]

Cannabis is the most frequently used federally illicit substance in pregnancy. The available human literature suggests that infants exposed to cannabis in pregnancy displ [...]

Transactive response DNA binding protein of 43 kDa (TDP-43) is a ubiquitously expressed nuclear protein involved in RNA metabolism and stress granule formation. Pathologi [...]

Amyloid beta (A?) plaques represent one of the classic hallmarks of Alzheimer's disease (AD) pathology in the brain. In rhesus macaques, these plaques start becoming prom [...]