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1.
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The human brain executes complex motor behaviors such as speech or running or juggling, but the specific cell types, gene expression patterns, and physiological profiles [...]
2022 |
Dissertation |
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2.
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Upon exposure to harmful microorganisms, hosts engage in protective molecular and behavioral immune responses, both of which are ultimately regulated by the nervous syste [...]
2022 |
Dissertation |
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3.
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Axons can represent the majority of a neuron's volume and are energetically demanding. Specialized glia ensheathe axons to insulate them and are believed to support axon [...]
2022 |
Dissertation |
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4.
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The majority of pharmaceutical drugs on the market target G protein coupled receptor (GPCRs); however, GPCR signaling and regulation adapt in response to environmental st [...]
2022 |
Dissertation |
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5.
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Nervous system development is a highly complex process involving multiple cellular transitions from that of an embryonic pluripotent state to that of a terminally differe [...]
2022 |
Dissertation |
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6.
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Glial cells perform paramount functions within the nervous system, closely monitoring and regulating neurons. Indispensable roles for glia have been elucidated in most as [...]
2022 |
Dissertation |
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7.
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Neurons communicate with each other either through electrical synapses formed by gap junctions, or by the synaptic release of neurotransmitters. Release of neurotransmitt [...]
2022 |
Dissertation |
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8.
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The bulk of this dissertation focuses on D2 receptor-GIRK channel coupling. Chapter topics include how structural variants of the D2 receptor modulate G protein engagemen [...]
2022 |
Dissertation |
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9.
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Fluorescent protein biosensors have become an important tool for neuroscience research. Highly optimized biosensors for Ca2+ are widely used to study neuronal activity in [...]
2022 |
Dissertation |
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10.
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The descending pain modulatory pathway exerts bidirectional control of ongoing nociceptive inputs traveling from the body to the brain. Despite a large body of work impli [...]
2021 |
Dissertation |
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