1.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor outcomes, partly due to dysfunctional vascularization and complex tumor-stromal interactions. Th [...]
2025-04-18 | Dissertation |
2.
This dissertation investigates the functional significance and therapeutic implications of novel extracellular domain (ECD) alterations in PDGFRA found in glioma. Specifi [...]
2025-04-25 | Dissertation |
3.

This thesis sought to identify and characterize novel drug targets in mycobacteria to aid in the discovery of better treatment options.

The author retains th [...]

2025-02-25 | Thesis |
4.
This dissertation investigates the molecular link between Parkinson's Disease and melanoma. Specifically, this work presents novel findings showing that alpha-synuclein f [...]
2025-03-22 | Dissertation |
5.
My work resulted in the discovery of a novel KATP channel pharmacochaperone, Aekatperone, through AI-driven virtual screening of the drug binding site using the Cryo-EM s [...]
2025-01-29 | Dissertation |
6.
This dissertation characterizes cross-reactive immunity to emerging alpahviruses such as chikungunya virus in the context of infection or vaccination, in various models.
2024-10-11 | Dissertation |
7.
Work presented in this dissertation describe mechanisms of oligomeric polydispersity and client-binding by various small heat shock proteins (alpha-crystallins, HSP16.5) [...]
2024-07-19 | Dissertation |
8.
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype characterized by a remarkable molecular heterogeneity. Currently, there are no effective [...]
2023-08-23 | Dissertation |