1.
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Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor outcomes, partly due to dysfunctional vascularization and complex tumor-stromal interactions. Th [...]
2025-04-18 |
Dissertation |
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2.
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This dissertation investigates the functional significance and therapeutic implications of novel extracellular domain (ECD) alterations in PDGFRA found in glioma. Specifi [...]
2025-04-25 |
Dissertation |
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3.
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This thesis sought to identify and characterize novel drug targets in mycobacteria to aid in the discovery of better treatment options. The author retains th [...]
2025-02-25 |
Thesis |
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4.
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This dissertation investigates the molecular link between Parkinson's Disease and melanoma. Specifically, this work presents novel findings showing that alpha-synuclein f [...]
2025-03-22 |
Dissertation |
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5.
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My work resulted in the discovery of a novel KATP channel pharmacochaperone, Aekatperone, through AI-driven virtual screening of the drug binding site using the Cryo-EM s [...]
2025-01-29 |
Dissertation |
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6.
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This dissertation characterizes cross-reactive immunity to emerging alpahviruses such as chikungunya virus in the context of infection or vaccination, in various models.
2024-10-11 |
Dissertation |
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7.
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Work presented in this dissertation describe mechanisms of oligomeric polydispersity and client-binding by various small heat shock proteins (alpha-crystallins, HSP16.5) [...]
2024-07-19 |
Dissertation |
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8.
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Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype characterized by a remarkable molecular heterogeneity. Currently, there are no effective [...]
2023-08-23 |
Dissertation |
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