In this case study, I demonstrate that CHCs are present in the blood of one patient with choroidal melanoma, lung adenocarcinoma, and a neuroendocrine tumor of the lung. [...]

Uveal melanoma (UM) is a rare but aggressive disease, with >50% of tumors propagating metastatic disease spread - associated with nearly uniform fatality. Despite sign [...]

Metabolic reprogramming is a fundamental hallmark of cancer, enabling tumors to sustain rapid proliferation and evade treatment by dynamically shifting nutrient acquisiti [...]

The work presented herein advances our understanding of neoplastic-immune hybrid cells as drivers of cancer progression and metastasis. My dissertation studies reveal sh [...]

Metastatic spread of cancer is responsible for the vast majority of cancer-related deaths highlighting the need to better understand the cellular mechanisms underlying th [...]