1.
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Lowenstein.Eve.2025
Identifying genetic targets of Tau toxicity in Frontotemporal Dementia Drosophila model
Lowenstein, Eve ; Kretzschmar, Doris ; Adey, Andrew ; Carbone, Lucia[...]
Current treatments for FTD mitigate some behavioral changes, but there are no therapies that prevent or slow the progression of the disease. Profiling the epigenetic chan [...]
2025-01-15 | Dissertation |
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2.
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4011_etd
Identifying the pathogenic mechanisms of swiss-cheese phenotypes to understand neuropathy target esterase associated disorders
Sunderhaus, Elizabeth ; Kretzschmar, Doris ; Morton, David B. ; Hayflick, Susan[...]
Neuropathy Target Esterase (NTE) is an enzyme localized to the ER that regulates Protein Kinase A (PKA) signaling and maintains lipid homeostasis. Exposure to a neurotox [...]
2018-05-01 | Dissertation |
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ResearchWeek.2020.Long.Dani
Investigating mechanisms that connect Alzheimer's disease with circadian disruptions
Long, Dani ; Kretzschmar, Doris
Recent research suggests that disruptions in circadian rhythms, including sleep-wake cycles, are early signs of Alzheimer's disease (AD) and may contribute to the patholo [...]
2020 | Abstract |
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