Acute myeloid leukemia, the cancer studied in this dissertation, is a malignancy that occurs within the myeloid branch of hematopoiesis. Hematopoiesis is the process by [...]

In these experiments, I begin to delineate the role of AML-derived exosomes in the regulation of the marrow microenvironment. Through electron and fluoresc [...]

Acute Myelogenous Leukemia (AML) is an aggressive cancer of the bone marrow that affects both adults and children alike. While many patients achieve remission following i [...]

Developmental origins of disease in the hematopoietic system remain poorly understood despite rising pediatric hematologic and immune disorders. Fanconi anemia (FA), the [...]