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Pioneer neurons establish the initial nervous system structure by extending axons toward distant targets, but their molecular distinction from follower neurons was previo [...]

Pioneer neurons are the first to extend their axons into a target tissue during nervous system development. Pioneer axon tracts act as a scaffold for subsequent extension [...]

The brain is a dense network of precisely interconnected cells called neurons. Our thoughts and behaviors require communication between billions of individual neurons tha [...]

Myelination in the CNS is essential for neuronal function, and oligodendrocytes achieve this by wrapping axons with multilayered myelin sheaths. We identify FBXW7 as a ke [...]