TMEM63B is a newly identified mechanosensor that is found in many dorsal root ganglion neurons. Dorsal root ganglion neurons are responsible somatosensation and one aspec [...]

Seizures are patterns of abnormal electrical activity in the brain that can result in altered sensory perception, loss of consciousness, and involuntary motor spasms. Epi [...]

During neural development cells must migrate to the appropriate destination and establish connections with the appropriate cell types. The cell adhesion molecule Dystrogl [...]

α2δ proteins (CACNA2D1-4) are auxiliary subunits to voltage-gated calcium channels (VGCCs), and they contribute to VGCC trafficking to the plasma membrane. However, there [...]

This dissertation characterizes the effects of endogenous opioid peptide enkephalin on excitability in the hippocampus. It also investigates the regulation of enkephalin [...]

Understanding the molecular and genetic identity of neuron types is prerequisite to tractable control and investigation of the behavioral relevance of discrete neuronal t [...]

The brain is a dense network of precisely interconnected cells called neurons. Our thoughts and behaviors require communication between billions of individual neurons tha [...]