Pancreatic Ductal Adenocarcinoma (PDAc) ranks among the top three most aggressive cancers in the United States and is projected to increase in incidence over the next few [...]

This cancer cell-intrinsic GOT2-PPARδ axis promotes spatial restriction of both CD4+ and CD8+ T cells from the tumor microenvironment, and fosters the immune-suppressive [...]

Chronic stress–driven sympathetic signaling influences cancer development by reshaping the tumor microenvironment (TME). This dissertation reviews how sympathetic nerves [...]

A dissertation discussing the role of mesenchymal kit ligand (kitl) in the pancreas, specifically in regards to healthy tissue homeostasis, tissue architecture, and disea [...]

The grim prognosis for pancreatic ductal adenocarcinoma (PDAC) patients impels an improved understanding of disease biology to facilitate the development of enhanced ther [...]