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In the absence of a prophylactic vaccine and curative strategies, the daily use of antiretroviral therapy (ART) is essential for preventing and maintaining HIV infection. [...]

In this dissertation I explore applications of antibodies and alpaca-derived antibody fragments, known as VHHs, to understand severe acute respiratory associated coronavi [...]

The human immune system’s relationship with cancer is incredibly complex. However, suggestions that the immune system can treat cancer have kept scientists searching for [...]

The immune system is a double-edged sword -- too little immunity we become susceptible to infection; too overactive and it leads to autoimmune diseases. This study guide [...]

There is an urgent unmet need for short-term interventions to prevent infection in infants exposed to HIV-1 at birth, who have higher mortality rates than infants infecte [...]

The flavivirus Zika virus (ZIKV) has extensive human health impact yet lacks vaccines and antiviral treatments in part due to gaps in understanding of the its infectious [...]

Novel anti-CB1 monoclonal antibodies, including an N-terminal binding antibody, were characterized and validated. These antibodies were then used to investigate the role [...]

The term “idiotypic specificity” was first proposed to designate a unique individual antigenic determinant of immunoglobulins which was not present on antibodies of the s [...]