Opioids such as morphine, oxycodone, and fentanyl effectively relieve acute and post-operative pain, but long-term use can lead to tolerance. Chronic opioid use leads to [...]

Therapeutic inertia in diabetes management is the failure to initiate or intensify pharmacological treatment when a patient's glycated hemoglobin (HbA1c) goals are not me [...]

This dissertation describes nocturnal sleep–wake patterns in adolescents undergoing chemotherapy and examines relationships among sleep, treatment‑related symptoms, and q [...]

The FDA has received millions of reports of adverse events over the last ten years. A clinician's ability to identify potential drug-drug interactions in routine practice [...]

Benzodiazepine receptor agonists (BZRA), which include brand names such as Valium, Xanax and Ambien, have been prescribed in clinical practice for decades. Despite their [...]

Opioids are highly effective analgesics but frequently lead to tolerance and dependence. Opioid effects are mediated by the μ‑opioid receptor (MOR), whose regulation thro [...]