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Given its central role in low-density lipoprotein (LDL) metabolism, there is interest in exploring proprotein convertase subtisilin/kexin type 9 (PCSK9) as a potential ci [...]
2020 |
Abstract |
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Immune checkpoint blockade (ICB) therapy targets checkpoint proteins to restore normal function to the immune system so that it can attack cancer cells. It is used succes [...]
2024 |
Abstract |
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The poly (ADP-ribose) polymerase (PARP) family catalyzes the post-translational modification known as ADP-ribosylation (ADPr) from donor molecule nicotinamide adenine din [...]
2017 |
Dissertation |
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This dissertation investigates the functional significance and therapeutic implications of novel extracellular domain (ECD) alterations in PDGFRA found in glioma. Specifi [...]
2025-04-25 |
Dissertation |
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