Obesity is a global health concern linked to chronic diseases such as diabetes, hypertension, and cancer, yet its underlying mechanisms remain unclear. Conjugated linolei [...]

Androgen hormones regulate the activity of myriad cells of the immune system and are strong drivers of sex differences in disease susceptibility, yet little is known of t [...]

Infectious diseases have historically been the leading cause of death worldwide. While cardiovascular disease has slowly overtaken infectious diseases as the leading caus [...]

Enormous data collection efforts and improvements in technology have made large-scale genome-wide association studies (GWAS) a promising approach to better understanding [...]

The collagen degradation mediated by host proteolytic enzymes, such as the metalloproteinases (MMPs), is strongly associated to the development of secondary caries at the [...]

West Nile virus (WNV) is an emerging arbovirus that disproportionately causes severe neurological disease in elderly individuals. This dissertation describes the developm [...]

Alcoholism is a debilitating disease, influenced by both biological (genetic) and environment factors. Unfortunately, the genetic determinants of risk remain largely un [...]