Transparency with illustration of brain stem, hypothalamus, anterior pituitary with neurons. Labeled 0616-007

G protein-coupled receptors (GPCRs) modulate the activity of neurons in many ways on both short and long timescales. These receptors initiate intracellular signaling ca [...]

Parkinson's disease (PD) is a neurodegenerative disorder characterized by declining motor function. While the etiology is not understood, a hallmark of PD is a loss of do [...]

The CDC reports that 52.9% of people who used MA in the last year have a MA use disorder. Quantitative trait locus mapping in selectively bred high and low MA drinking (M [...]

Dopamine neurons in the ventral tegmental area (VTA) and substantia nigra regulate motivation and reward, and their disinhibition by opioids is a critical step in addicti [...]

Dopamine neurons in the substantia nigra (SN) are strongly regulated by small-conductance calcium-activated potassium (SK) channels, previously attributed solely to SK3 e [...]