Acute cardiac injury with renal injury (acute cardiorenal syndrome) can induce chronic kidney disease (CKD), but mechanisms by which heart injury signals to kidney are un [...]

Obesity is a major public health concern linked to numerous comorbidities, including nonalcoholic fatty liver disease (NAFLD), which can progress to cirrhosis and liver f [...]

The increased production of reactive oxygen species (ROS) is a hallmark of fibrosis and cancer. In fibrosis, the release of ROS along with secretion of pro-fibrotic cyt [...]

An estimated 2.7-4 million people in the United States have been infected with the hepatitis C virus (HCV), of those, about 3.2 million have current HCV infections. Howe [...]

As individuals with Cystic Fibrosis (CF) live longer, they can develop complications such as Cystic Fibrosis Related Diabetes (CFRD), the most common complication seen in [...]

Patients are prioritized for liver transplantation (LT) by their anticipated 904-day waitlist mortality using the MELD score; however, the MELD underestimates waitlist m [...]

This publication provides an overview of pediatric care at Doernbecher Children’s Hospital, previously called the Doernbecher Memorial Hospital for Children, from 1926 to [...]

Cystic fibrosis is caused by mutations in CFTR, a protein largely degraded by the proteasome, with the common ΔF508 mutation undergoing near-complete degradation. To iden [...]

Membrane protein folding is a fundamental yet poorly understood process in cell biology, despite membrane proteins comprising a substantial portion of cellular proteomes [...]

This first issue of 2026 highlights the scholarly vitality of the OHSU School of Dentistry’s academic community by showcasing work from students, faculty and staff acr [...]