Androgen hormones regulate the activity of myriad cells of the immune system and are strong drivers of sex differences in disease susceptibility, yet little is known of t [...]

Sex differences in disease susceptibility, including infection, cancer, and autoimmunity, have been well-characterized, with males generally being more susceptible to inf [...]

In the absence of a prophylactic vaccine and curative strategies, the daily use of antiretroviral therapy (ART) is essential for preventing and maintaining HIV infection. [...]

Kaposi’s sarcoma–associated herpesvirus (KSHV) uses immune‑evasion strategies to support successful infection, including the activity of its viral E3 ubiquitin ligase, K5 [...]

Caenorhabditis elegans, a natural bacterivore, has proven to be a fruitful model organism for studying host-pathogen interactions, feeding behaviors, and learning. Previo [...]

A low molecular weight non-precipitating antigen from timothy pollen extract, Antigen G (AgD), is monovalent for the major antigen which induces reaginic antibody in huma [...]

PARPs are a family of 17 proteins that regulate a diverse range of cellular processes through the transfer of ADP-ribose from NAD+ to amino acids on protein targets, a pr [...]

What properties, at the level of individual molecules, are responsible for allowing the adaptive immune system to differentiate cancerous cells from surrounding healthy t [...]

Cachexia is a devastating metabolic syndrome affecting up to 80% of patients with pancreatic ductal adenocarcinoma. Cardiac wasting and injury are common manifestations, [...]