Genetic heterogeneity makes clinical interventions challenging for patients with acute myeloid leukemia (AML). Identifying and targeting common microenvironment-driven pa [...]

Immune checkpoint blockade (ICB) has revolutionized the ways in which we treat some cancers, producing durable responses. However, many patients fail to respond to ICB. I [...]

Ricin is a ribotoxic stressor that blocks protein synthesis and activates stress‑activated protein kinases, but its mechanisms of inducing inflammation remain unclear. Be [...]

Respiratory viral infections trigger most asthma exacerbations by disrupting neural airway control. Normally, M2 muscarinic receptors on parasympathetic neurons inhibit a [...]